ULTOMIRIS® Infusion Scheme: weight-based dosing regimen1

ULTOMIRIS® : Infuse your patients with up to 8 weeks of freedom*

Patients Initiating ULTOMIRIS® with no prior treatment

Patients Initiating ULTOMIRIS® following eculizumab therapy

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Loading dose

Loading dose of ULTOMIRIS® should be administered 2 weeks after the last eculizumab infusion

Maintenance doses are administered once every 4 or 8 weeks (depending on body weight), starting 2 weeks after the loading dose

Weight based dosing regimen

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Body Weight Range (kg)

Loading Dose (mg)

Maintenance Dosing (mg)

Dosing Interval

≥10 to <20

600

600

Every 4 weeks

≥20 to <30

900

2100

≥30 to <40

1200

2700

≥40 to <60

2400

3000

Every 8 weeks

≥60 to <100

2700

3300

≥100

3000

3600

*Starting 2 weeks after the loading dose, maintenance doses are administered once every 4 or 8 weeks (depending on body weight) giving adult/pediatric patients the possibility to live dialysis- free.